Yes, time to use the adjustments in the clasp now. You can only go so far with the links before you have to start using the clasp adjustments. My 36mm Explorer 1 is like that. I have all the links removed and the clasp is adjusted 2 holes in.
With my 1680, however, I have not needed to do any adjustments with the clasp. I don't know if that is due to the watch head being of a different size or what, but it wears very comfortably with just the links removed.
Worst case scenario is there is a permanent solution that will mangle the link you are removing. You can separate a permanent link and remove it. You need two pliers and a lot of force, but it can be done. Rolex has a tool for doing this but a set of pliers can work. The link will be completely trashed so if you ever need to replace it you'll have to reach out to other members here to see if anyone has a spare link they can give you.